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Software

Free/ Commercial

Website

Functions of the software

Visualization

1. Rasmol Free http://www.bernstein-plus-sons.com/ software/rasmol
  • Popular and versatile molecular graphics viewing program, excellent for viewing macromolecular structures
  • Needs command line scripting
2. Weblab lite Free http://www.accelrys.com/viewer/t
  • Molecular Visualization, Analysis and structural information
  • No command line scripting

Suite

3. Bioedit Freeware http://www.mbio.ncsu.edu/BioEdit/bioedit.html
  • Biological sequence alignment editor
  • Automated ClustalW alignment
  • Plasmid drawing and annotation
  • Accessory application configuration
  • Restriction mapping
  • RNA comparative analysis tools
  • Graphical matrix data viewing tools
  • Shaded alignment figures
  • Translation-based nucleic acid alignment
  • ABI trace viewing, editing and printing
  • Web integration
4. Antherpr

ot

Freeware http://antheprot-pbil.ibep.fr/ie_sommaire.html
  • Sequence information
  • Sequence edition
  • Dot matrix plot
  • Fasta/Blast
  • Sites/signatures detection
  • Physico-chemical profiles
  • Secondary structure prediction
  • Helical wheel projections
  • Binary alignments (dynamic programming NW algorithm)
  • Multiple alignments
  • Prediction of signal peptide and cleavage site
  • 3D display of molecules
  • Amphiphilicity
  • Titration curve
5.

DNA tools

Freeware (but license is needed) http://www.dnatools.dk
  • Handling and analysis of nucleotide and protein sequences
  • Sequence editing and annotation, restriction mapping, translation, batch blast search, codon analysis, primer design and ordering handling
  • Analysis of small EST projects and SAGE data

Miscellaneous

1.

Winpep

Freeware http://www.ipw.agrl.ethz.ch/~lhennig/winpep.html
  • Determination of length and amino acid composition
  • Calculation of the molecular weight
  • Estimation of the isoelectric point (IEP)
  • Estimation of molar absorption coefficients
  • Batch analysis of multiple sequences
  • Simulation of sequences specific cleavage
  • Identification of potential post-translational modifications
  • Searching for sequence motifs
  • Helical wheel display of amino acid sequences
  • Hydropathy plot display of sequences
  • Display of the domain structure of proteins.
2.

DNA for windows

Freeware http://website.lineone.net/~molbio
  • Easy manipulation of sequences - removal of ‘junk’ text, reverse, complement, trim, etc.
  • Restriction enzyme analysis - custom groups of enzymes
  • Translation of DNA to protein
  • Calculates mass of selected protein.
  • Easy multiple sequence alignment
  • Automatic contig assembly-using interface to CAP program
  • Dot-Plot analysis
3.

ClustalX

Freeware Http://inn-prot.weizmann.ac.il/ software/ClustalX.html
  • Multiple sequence alignment program with user friendly interface
4.

Cluster

Freeware, but needs license Http://rana.lbl.gov/EisenSoftware.htm
  • Cluster analysis and microarray dataset processing–hierarchical clustering, self-organizing maps (SOMs), k-means clustering, principal componenet analysis
5.

Treeview

Freeware, but needs license http://rana.lbl.gov/EisenSoftware.htm
  • Graphically representation of clustering and other analyses from Cluster.
6.

Treeview

Freeware http://taxonomy.zoology.gla.ac.uk /rod/treeview.html
  • Phylogeny tree drawing software
7.

LINDO

Commercial/demo version www.lindo.com
  • Linear Programming Package, suitable for optimization
  • Can be used for flux balance analysis (FBA).

 

 

 

 

 

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